Next Article in Journal
NADPH Oxidase Biology and the Regulation of Tyrosine Kinase Receptor Signaling and Cancer Drug Cytotoxicity
Previous Article in Journal
Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
Due to scheduled maintaince work on one of the switches in our server center, our websites www.mdpi.com and susy.mdpi.com may experience short service dirsuptions of up to 5 minutes on 30 January 2015 00:00 PM EST time.
Int. J. Mol. Sci. 2013, 14(2), 3671-3682; doi:10.3390/ijms14023671
Article

Synthesis and Characterization of the Inclusion Complex of β-cyclodextrin and Azomethine

, * ,
 and
Received: 8 December 2012 / Revised: 14 January 2013 / Accepted: 25 January 2013 / Published: 7 February 2013
View Full-Text   |   Download PDF [343 KB, uploaded 19 June 2014]   |   Browse Figures
Abstract: A β-cyclodextrin (β-Cyd) inclusion complex containing azomethine as a guest was prepared by kneading method with aliquot addition of ethanol. The product was characterized by Fourier Transform Infrared (FTIR) spectrometer, 1H Nuclear Magnetic Resonance (1H NMR) and Thermogravimetric Analyzer (TGA), which proves the formation of the inclusion complex where the benzyl part of azomethine has been encapsulated by the hydrophobic cavity of β-Cyd. The interaction of β-Cyd and azomethine was also analyzed by means of spectrometry by UV-Vis spectrophotometer to determine the formation constant. The formation constant was calculated by using a modified Benesi-Hildebrand equation at 25 °C. The apparent formation constant obtained was 1.29 × 104 L/mol. Besides that, the stoichiometry ratio was also determined to be 1:1 for the inclusion complex of β-Cyd with azomethine.
Keywords: β-cyclodextrin; azomethine; Schiff bases; inclusion complex β-cyclodextrin; azomethine; Schiff bases; inclusion complex
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Sambasevam, K.P.; Mohamad, S.; Sarih, N.M.; Ismail, N.A. Synthesis and Characterization of the Inclusion Complex of β-cyclodextrin and Azomethine. Int. J. Mol. Sci. 2013, 14, 3671-3682.

AMA Style

Sambasevam KP, Mohamad S, Sarih NM, Ismail NA. Synthesis and Characterization of the Inclusion Complex of β-cyclodextrin and Azomethine. International Journal of Molecular Sciences. 2013; 14(2):3671-3682.

Chicago/Turabian Style

Sambasevam, Kavirajaa P.; Mohamad, Sharifah; Sarih, Norazilawati M.; Ismail, Nor A. 2013. "Synthesis and Characterization of the Inclusion Complex of β-cyclodextrin and Azomethine." Int. J. Mol. Sci. 14, no. 2: 3671-3682.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert