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Int. J. Mol. Sci. 2013, 14(11), 21899-21942; doi:10.3390/ijms141121899
Review

Solid Lipid Nanoparticle-Based Calix[n]arenes and Calix-Resorcinarenes as Building Blocks: Synthesis, Formulation and Characterization

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Received: 2 September 2013; in revised form: 7 October 2013 / Accepted: 9 October 2013 / Published: 5 November 2013
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Abstract: Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. This paper presents an overview about the use of calix[n]arenes and calix-resorcinarenes in the formulation of SLNs. Because of their specific inclusion capability both in the intraparticle spaces and in the host cavities as well as their capacity for functionalization, these colloidal nanostructures represent excellent tools for the encapsulation of different active pharmaceutical ingredients (APIs) in the area of drug targeting, cosmetic additives, contrast agents, etc. Various synthetic routes to the supramolecular structures will be given. These various routes lead to the formulation of the corresponding SLNs. Characterization, properties, toxicological considerations as well as numerous corresponding experimental studies and analytical methods will be also exposed and discussed.
Keywords: solid lipid nanoparticles; calix[n]arenes; calix-resorcinarenes; encapsulation; colloids; supramolecular; nanocarriers solid lipid nanoparticles; calix[n]arenes; calix-resorcinarenes; encapsulation; colloids; supramolecular; nanocarriers
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Montasser, I.; Shahgaldian, P.; Perret, F.; Coleman, A.W. Solid Lipid Nanoparticle-Based Calix[n]arenes and Calix-Resorcinarenes as Building Blocks: Synthesis, Formulation and Characterization. Int. J. Mol. Sci. 2013, 14, 21899-21942.

AMA Style

Montasser I, Shahgaldian P, Perret F, Coleman AW. Solid Lipid Nanoparticle-Based Calix[n]arenes and Calix-Resorcinarenes as Building Blocks: Synthesis, Formulation and Characterization. International Journal of Molecular Sciences. 2013; 14(11):21899-21942.

Chicago/Turabian Style

Montasser, Imed; Shahgaldian, Patrick; Perret, Florent; Coleman, Anthony W. 2013. "Solid Lipid Nanoparticle-Based Calix[n]arenes and Calix-Resorcinarenes as Building Blocks: Synthesis, Formulation and Characterization." Int. J. Mol. Sci. 14, no. 11: 21899-21942.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert