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Int. J. Mol. Sci. 2013, 14(10), 20359-20385; doi:10.3390/ijms141020359
Review

HKT Transporters—State of the Art

1,* , 2
 and 1
1 Vrije Universiteit Amsterdam, Faculty Earth and Life Sciences, Department of Structural Biology, Amsterdam NL-1081 HV, The Netherlands 2 Vrije Universiteit Amsterdam, Faculty Earth and Life Sciences, Systems Ecology, Department of Ecological Science, Amsterdam NL-1081 HV, The Netherlands
* Author to whom correspondence should be addressed.
Received: 15 July 2013 / Revised: 15 August 2013 / Accepted: 18 September 2013 / Published: 14 October 2013
(This article belongs to the Section Bioinorganic Chemistry)
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Abstract

The increase in soil salinity poses a serious threat to agricultural yields. Under salinity stress, several Na+ transporters play an essential role in Na+ tolerance in plants. Amongst all Na+ transporters, HKT has been shown to have a crucial role in both mono and dicotyledonous plants in the tolerance to salinity stress. Here we present an overview of the physiological role of HKT transporters in plant Na+ homeostasis. HKT regulation and amino acids important to the correct function of HKT transporters are reviewed. The functions of the most recently characterized HKT members from both HKT1 and HKT2 subfamilies are also discussed. Topics that still need to be studied in future research (e.g., HKT regulation) as well as research suggestions (e.g., generation of HKT mutants) are addressed.
Keywords: abiotic stress; salinity stress; HKT transporters abiotic stress; salinity stress; HKT transporters
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Almeida, P.; Katschnig, D.; de Boer, A.H. HKT Transporters—State of the Art. Int. J. Mol. Sci. 2013, 14, 20359-20385.

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