Int. J. Mol. Sci. 2013, 14(1), 496-514; doi:10.3390/ijms14010496
Article

Chemical Constituents from Andrographis echioides and Their Anti-Inflammatory Activity

1,†email, 2,†email, 3,†email, 4email, 5email, 1email and 1,4,6,* email
Received: 12 November 2012; in revised form: 11 December 2012 / Accepted: 17 December 2012 / Published: 27 December 2012
(This article belongs to the Special Issue Plant-Derived Pharmaceuticals by Molecular Farming 2012)
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Abstract: Phytochemical investigation of the whole plants of Andrographis echioides afforded two new 2'-oxygenated flavonoids (1) and (2), two new phenyl glycosides (3) and (4), along with 37 known structures. The structures of new compounds were elucidated by spectral analysis and chemical transformation studies. Among the isolated compounds, (12) and (619) were subjected into the examination for their iNOS inhibitory bioactivity. The structure-activity relationships of the flavonoids for their inhibition of NO production were also discussed.
Keywords: Andrographis echioides; flavonoid; anti-inflammatory; iNOS
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MDPI and ACS Style

Shen, D.-Y.; Juang, S.-H.; Kuo, P.-C.; Huang, G.-J.; Chan, Y.-Y.; Damu, A.G.; Wu, T.-S. Chemical Constituents from Andrographis echioides and Their Anti-Inflammatory Activity. Int. J. Mol. Sci. 2013, 14, 496-514.

AMA Style

Shen D-Y, Juang S-H, Kuo P-C, Huang G-J, Chan Y-Y, Damu AG, Wu T-S. Chemical Constituents from Andrographis echioides and Their Anti-Inflammatory Activity. International Journal of Molecular Sciences. 2013; 14(1):496-514.

Chicago/Turabian Style

Shen, De-Yang; Juang, Shin-Hun; Kuo, Ping-Chung; Huang, Guan-Jhong; Chan, Yu-Yi; Damu, Amooru G.; Wu, Tian-Shung. 2013. "Chemical Constituents from Andrographis echioides and Their Anti-Inflammatory Activity." Int. J. Mol. Sci. 14, no. 1: 496-514.


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