Int. J. Mol. Sci. 2011, 12(9), 5844-5852; doi:10.3390/ijms12095844
Article

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

Samuel I. A. Cohen, Michele Vendruscolo, Christopher M. Dobson and Tuomas P. J. Knowles* email
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
* Author to whom correspondence should be addressed.
Received: 2 August 2011; in revised form: 30 August 2011 / Accepted: 30 August 2011 / Published: 9 September 2011
(This article belongs to the Special Issue Protein Aggregation)
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Abstract: We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed.
Keywords: protein; aggregation; amyloid

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MDPI and ACS Style

Cohen, S.I.A.; Vendruscolo, M.; Dobson, C.M.; Knowles, T.P.J. Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments. Int. J. Mol. Sci. 2011, 12, 5844-5852.

AMA Style

Cohen SIA, Vendruscolo M, Dobson CM, Knowles TPJ. Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments. International Journal of Molecular Sciences. 2011; 12(9):5844-5852.

Chicago/Turabian Style

Cohen, Samuel I. A.; Vendruscolo, Michele; Dobson, Christopher M.; Knowles, Tuomas P. J. 2011. "Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments." Int. J. Mol. Sci. 12, no. 9: 5844-5852.

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