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Int. J. Mol. Sci. 2011, 12(9), 5844-5852; doi:10.3390/ijms12095844

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
Author to whom correspondence should be addressed.
Received: 2 August 2011 / Revised: 30 August 2011 / Accepted: 30 August 2011 / Published: 9 September 2011
(This article belongs to the Special Issue Protein Aggregation)
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We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting cases of a reaction starting from purely soluble material and for a reaction where no new growth nuclei are formed.
Keywords: protein; aggregation; amyloid protein; aggregation; amyloid
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Cohen, S.I.A.; Vendruscolo, M.; Dobson, C.M.; Knowles, T.P.J. Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments. Int. J. Mol. Sci. 2011, 12, 5844-5852.

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