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Int. J. Mol. Sci. 2011, 12(7), 4395-4413; doi:10.3390/ijms12074395
Review

Enabling Anticancer Therapeutics by Nanoparticle Carriers: The Delivery of Paclitaxel

1
, 1
 and 1,2,*
Received: 27 April 2011; in revised form: 9 June 2011 / Accepted: 15 June 2011 / Published: 7 July 2011
(This article belongs to the Special Issue Bioactive Nanoparticles)
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Abstract: Anticancer drugs, such as paclitaxel (PTX), are indispensable for the treatment of a variety of malignancies. However, the application of most drugs is greatly limited by the low water solubility, poor permeability, or high efflux from cells. Nanoparticles have been widely investigated to enable drug delivery due to their low toxicity, sustained drug release, molecular targeting, and additional therapeutic and imaging functions. This review takes paclitaxel as an example and compares different nanoparticle-based delivery systems for their effectiveness in cancer chemotherapy.
Keywords: nanomaterials; anticancer drugs; paclitaxel; drug carrier; drug delivery nanomaterials; anticancer drugs; paclitaxel; drug carrier; drug delivery
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Liu, Y.; Zhang, B.; Yan, B. Enabling Anticancer Therapeutics by Nanoparticle Carriers: The Delivery of Paclitaxel. Int. J. Mol. Sci. 2011, 12, 4395-4413.

AMA Style

Liu Y, Zhang B, Yan B. Enabling Anticancer Therapeutics by Nanoparticle Carriers: The Delivery of Paclitaxel. International Journal of Molecular Sciences. 2011; 12(7):4395-4413.

Chicago/Turabian Style

Liu, Yongjin; Zhang, Bin; Yan, Bing. 2011. "Enabling Anticancer Therapeutics by Nanoparticle Carriers: The Delivery of Paclitaxel." Int. J. Mol. Sci. 12, no. 7: 4395-4413.



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