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Int. J. Mol. Sci. 2011, 12(10), 7186-7198; doi:10.3390/ijms12107186

Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies

Department of Chemistry, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa
Author to whom correspondence should be addressed.
Received: 5 August 2011 / Revised: 30 September 2011 / Accepted: 11 October 2011 / Published: 21 October 2011
(This article belongs to the Section Biomaterial Sciences)
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Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined. View Full-Text
Keywords: metal complexes; diisopropylthiourea; antibacterial; drug resistance metal complexes; diisopropylthiourea; antibacterial; drug resistance

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Ajibade, P.A.; Zulu, N.H. Metal Complexes of Diisopropylthiourea: Synthesis, Characterization and Antibacterial Studies. Int. J. Mol. Sci. 2011, 12, 7186-7198.

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