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Int. J. Mol. Sci. 2011, 12(10), 6635-6644; doi:10.3390/ijms12106635

Quantitative Comparative Analysis of the Bio-Active and Toxic Constituents of Leaves and Spikes of Schizonepeta tenuifolia at Different Harvesting Times

Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210046, China
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Received: 26 July 2011 / Revised: 26 September 2011 / Accepted: 28 September 2011 / Published: 10 October 2011
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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Abstract

A GC-MS-Selected Ion Monitoring (SIM) detection method was developed for simultaneous determination of four monoterpenes: (-)-menthone, (+)-pulegone, (-)-limonene and (+)-menthofuran as the main bio-active and toxic constituents, and four other main compounds in the volatile oils of Schizonepeta tenuifolia (ST) leaves and spikes at different harvesting times. The results showed that the method was simple, sensitive and reproducible, and that harvesting time was a possible key factor in influencing the quality of ST leaves, but not its spikes. The research might be helpful for determining the harvesting time of ST samples and establishing a validated method for the quality control of ST volatile oil and other relative products. View Full-Text
Keywords: Schizonepeta tenuifolia; menthone; pulegone; limonene; menthofuran; harvesting time Schizonepeta tenuifolia; menthone; pulegone; limonene; menthofuran; harvesting time
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Yu, S.; Chen, Y.; Zhang, L.; Shan, M.; Tang, Y.; Ding, A. Quantitative Comparative Analysis of the Bio-Active and Toxic Constituents of Leaves and Spikes of Schizonepeta tenuifolia at Different Harvesting Times. Int. J. Mol. Sci. 2011, 12, 6635-6644.

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