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Nanocharacterization in Dentistry
Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, CA, USA
California NanoSystems Institute, University of California, Los Angeles 90095, CA, USA
International Center for Materials Nanoarchitectonics Satellite (MANA), National Institute for Materials Science (NIMS), Tsukuba 305-0047, Japan
* Author to whom correspondence should be addressed.
Received: 19 March 2010; in revised form: 5 June 2010 / Accepted: 7 June 2010 / Published: 17 June 2010
Abstract: About 80% of US adults have some form of dental disease. There are a variety of new dental products available, ranging from implants to oral hygiene products that rely on nanoscale properties. Here, the application of AFM (Atomic Force Microscopy) and optical interferometry to a range of dentistry issues, including characterization of dental enamel, oral bacteria, biofilms and the role of surface proteins in biochemical and nanomechanical properties of bacterial adhesins, is reviewed. We also include studies of new products blocking dentine tubules to alleviate hypersensitivity; antimicrobial effects of mouthwash and characterizing nanoparticle coated dental implants. An outlook on future “nanodentistry” developments such as saliva exosomes based diagnostics, designing biocompatible, antimicrobial dental implants and personalized dental healthcare is presented.
Keywords: nano-characterization; dentistry; biofilms; bacterial adhesins; implants; dentine tubule; afm; interferometry; nanodentistry
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MDPI and ACS Style
Sharma, S.; Cross, S.E.; Hsueh, C.; Wali, R.P.; Stieg, A.Z.; Gimzewski, J.K. Nanocharacterization in Dentistry. Int. J. Mol. Sci. 2010, 11, 2523-2545.
Sharma S, Cross SE, Hsueh C, Wali RP, Stieg AZ, Gimzewski JK. Nanocharacterization in Dentistry. International Journal of Molecular Sciences. 2010; 11(6):2523-2545.
Sharma, Shivani; Cross, Sarah E.; Hsueh, Carlin; Wali, Ruseen P.; Stieg, Adam Z.; Gimzewski, James K. 2010. "Nanocharacterization in Dentistry." Int. J. Mol. Sci. 11, no. 6: 2523-2545.