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Int. J. Mol. Sci. 2010, 11(1), 124-139; doi:10.3390/ijms11010124
Review

The Diverse Applications of Cladistic Analysis of Molecular Evolution, with Special Reference to Nested Clade Analysis

Received: 25 November 2009 / Revised: 6 January 2010 / Accepted: 6 January 2010 / Published: 8 January 2010
(This article belongs to the Special Issue Cladistic Analysis and Molecular Evolution)
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Abstract

The genetic variation found in small regions of the genomes of many species can be arranged into haplotype trees that reflect the evolutionary genealogy of the DNA lineages found in that region and the accumulation of mutations on those lineages. This review demonstrates some of the many ways in which clades (branches) of haplotype trees have been applied in recent years, including the study of genotype/phenotype associations at candidate loci and in genome-wide association studies, the phylogeographic history of species, human evolution, the conservation of endangered species, and the identification of species.
Keywords: association studies; phylogeography; human evolution; conservation biology; species association studies; phylogeography; human evolution; conservation biology; species
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Templeton, A.R. The Diverse Applications of Cladistic Analysis of Molecular Evolution, with Special Reference to Nested Clade Analysis. Int. J. Mol. Sci. 2010, 11, 124-139.

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