Int. J. Mol. Sci. 2009, 10(6), 2611-2632; doi:10.3390/ijms10062611
Review

The Eukaryotic Cell Originated in the Integration and Redistribution of Hyperstructures from Communities of Prokaryotic Cells Based on Molecular Complementarity

1 AMMIS Laboratory, EA 3829, University of Rouen, Mont Saint Aignan, 76821 France 2 Department of Physiology, 2174 BPS, Michigan State University, East Lansing, MI 48824, USA
* Author to whom correspondence should be addressed.
Received: 21 April 2009; in revised form: 25 May 2009 / Accepted: 3 June 2009 / Published: 4 June 2009
(This article belongs to the Special Issue Origin of Life)
PDF Full-text Download PDF Full-Text [129 KB, uploaded 4 June 2009 14:48 CEST]
Abstract: In the “ecosystems-first” approach to the origins of life, networks of non-covalent assemblies of molecules (composomes), rather than individual protocells, evolved under the constraints of molecular complementarity. Composomes evolved into the hyperstructures of modern bacteria. We extend the ecosystems-first approach to explain the origin of eukaryotic cells through the integration of mixed populations of bacteria. We suggest that mutualism and symbiosis resulted in cellular mergers entailing the loss of redundant hyperstructures, the uncoupling of transcription and translation, and the emergence of introns and multiple chromosomes. Molecular complementarity also facilitated integration of bacterial hyperstructures to perform cytoskeletal and movement functions.
Keywords: composome; intron; motility; molecular complementarity; hyperstructure; origin of life; evolution; cytoskeleton; mutualism; symbiosis; ecology; ecosystem

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Norris, V.; Root-Bernstein, R. The Eukaryotic Cell Originated in the Integration and Redistribution of Hyperstructures from Communities of Prokaryotic Cells Based on Molecular Complementarity. Int. J. Mol. Sci. 2009, 10, 2611-2632.

AMA Style

Norris V, Root-Bernstein R. The Eukaryotic Cell Originated in the Integration and Redistribution of Hyperstructures from Communities of Prokaryotic Cells Based on Molecular Complementarity. International Journal of Molecular Sciences. 2009; 10(6):2611-2632.

Chicago/Turabian Style

Norris, Vic; Root-Bernstein, Robert. 2009. "The Eukaryotic Cell Originated in the Integration and Redistribution of Hyperstructures from Communities of Prokaryotic Cells Based on Molecular Complementarity." Int. J. Mol. Sci. 10, no. 6: 2611-2632.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert