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Int. J. Mol. Sci. 2009, 10(4), 1853-1871; doi:10.3390/ijms10041853

On the Free Energy That Drove Primordial Anabolism

The Protein Chemistry Group, Witten/Herdecke University, Stockumer Str. 10, 58448 Witten, Germany
Received: 26 March 2009 / Revised: 16 April 2009 / Accepted: 20 April 2009 / Published: 22 April 2009
(This article belongs to the Special Issue Origin of Life)
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A key problem in understanding the origin of life is to explain the mechanism(s) that led to the spontaneous assembly of molecular building blocks that ultimately resulted in the appearance of macromolecular structures as they are known in modern biochemistry today. An indispensable thermodynamic prerequisite for such a primordial anabolism is the mechanistic coupling to processes that supplied the free energy required. Here I review different sources of free energy and discuss the potential of each form having been involved in the very first anabolic reactions that were fundamental to increase molecular complexity and thus were essential for life.
Keywords: Primordial Anabolism; Origin of Life; Free Energy Primordial Anabolism; Origin of Life; Free Energy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Kaufmann, M. On the Free Energy That Drove Primordial Anabolism. Int. J. Mol. Sci. 2009, 10, 1853-1871.

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