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Int. J. Mol. Sci. 2009, 10(2), 589-615; doi:10.3390/ijms10020589

Biodegradable Polydepsipeptides

School of Chemical Engineering and Technology, Tianjin University / Weijin Road 92, 300072 Tianjin, P.R. China
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Received: 5 January 2009 / Revised: 10 February 2009 / Accepted: 13 February 2009 / Published: 13 February 2009
(This article belongs to the Special Issue Biodegradability of Materials)
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Abstract

This paper reviews the synthesis, characterization, biodegradation and usage of bioresorbable polymers based on polydepsipeptides. The ring-opening polymerization of morpholine-2,5-dione derivatives using organic Sn and enzyme lipase is discussed. The dependence of the macroscopic properties of the block copolymers on their structure is also presented. Bioresorbable polymers based on polydepsipeptides could be used as biomaterials in drug controlled release, tissue engineering scaffolding and shape-memory materials.
Keywords: Polydepsipeptides; morpholine-2; 5-dione; biomaterials; biodegradation; ring-opening polymerization Polydepsipeptides; morpholine-2; 5-dione; biomaterials; biodegradation; ring-opening polymerization
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Feng, Y.; Guo, J. Biodegradable Polydepsipeptides. Int. J. Mol. Sci. 2009, 10, 589-615.

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