Trichothecenes in Cereal Grains

doi:10.3390/ijms10010147

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Int. J. Mol. Sci. 2009, 10(1), 147-173; doi:10.3390/ijms10010147

Review

Trichothecenes in Cereal Grains

Nora A. Foroud ^1,2 and François Eudes ¹^,*

¹ Lethbridge Research Centre, Agriculture and Agri-Food Canada, 5403 1st Avenue South, Lethbridge, AB, Canada T1J 4B1 ² Michael Smith Laboratories, The University of British Columbia, #301 - 2185 East Mall, Vancouver, B.C., Canada V6T 1Z4

* Author to whom correspondence should be addressed.

Received: 7 November 2008; in revised form: 16 December 2008 / Accepted: 5 January 2009 / Published: 6 January 2009

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)

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Abstract: Trichothecenes are sesquiterpenoid mycotoxins associated with fusarium head blight (FHB) of cereals, with worldwide economic and health impacts. While various management strategies have been proposed to reduce the mycotoxin risk, breeding towards FHB-resistance appears to be the most effective means to manage the disease, and reduce trichothecene contamination of cereal-based food products. This review provides a brief summary of the trichothecene synthesis in Fusarium species, their toxicity in plants and humans, followed by the current methods of screening and breeding for resistance to FHB and trichothecene accumulation.

Keywords: Trichothecene; fusarium head blight; cereal grain

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Cite This Article

MDPI and ACS Style

Foroud, N.A.; Eudes, F. Trichothecenes in Cereal Grains. Int. J. Mol. Sci. 2009, 10, 147-173.

AMA Style

Foroud N.A., Eudes F. Trichothecenes in Cereal Grains. International Journal of Molecular Sciences. 2009; 10(1):147-173.

Chicago/Turabian Style

Foroud, Nora A.; Eudes, François. 2009. "Trichothecenes in Cereal Grains." Int. J. Mol. Sci. 10, no. 1: 147-173.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI Publishing, Basel, Switzerland RSS E-Mail Table of Contents Alert