Molecules 2004, 9(6), 472-479; doi:10.3390/90600472
Article

Toward Pyridine-Fused Selenium-Containing Antioxidants

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Received: 17 February 2004; Accepted: 21 February 2004 / Published: 31 May 2004
(This article belongs to the Special Issue RACI 2003 symposium)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Photolysis of the thiohydroximate ester derivative 21 of 2-carboethoxy-2-(2- (benzylseleno)pyridin-3-yl)tridecylcarboxylic acid (20) affords 2-dodecyl-2- carboethoxy-2,3-dihydroselenolo[2,3-b]pyridine (22) in 89% yield in a process presumably involving intramolecular homolytic substitution by a tertiary alkyl radical at selenium with loss of a benzyl radical. Work toward extending this methodology to the preparation of pyridine-fused selenium analogues of antioxidants is described.
Keywords: Free radical; homolytic substitution; selenium; antioxidants.
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MDPI and ACS Style

Fenner, T.; Schiesser, C.H. Toward Pyridine-Fused Selenium-Containing Antioxidants. Molecules 2004, 9, 472-479.

AMA Style

Fenner T, Schiesser CH. Toward Pyridine-Fused Selenium-Containing Antioxidants. Molecules. 2004; 9(6):472-479.

Chicago/Turabian Style

Fenner, Tahli; Schiesser, Carl H. 2004. "Toward Pyridine-Fused Selenium-Containing Antioxidants." Molecules 9, no. 6: 472-479.


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