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Molecules 2004, 9(3), 50-66; doi:10.3390/90300050
Review

New Synthetic Routes to Furocoumarins and Their Analogs: A Review

Department of Organic Chemistry, D. Mendeleev University of Chemical Technology of Russia 125047, Moscow, Russia
Received: 27 January 2004 / Accepted: 25 February 2004 / Published: 28 February 2004
(This article belongs to the Special Issue Biologically Relevant Heterocyclic Compounds)

Abstract

Many furocoumarins and their analogs possess a prominent photobiological activity. Some of them are successfully used as drugs in phototherapy of skin diseases. Fries rearrangement of acyloxyheteroarenes, condensation of acylhydroxyheteroarenes with α-carbonyl compounds under base catalysis and transformations of dihydrofurocoumarinones are new trends in synthesis of furocoumarins and their analogs.
Keywords: Furocoumarins; furocoumarin analogs; psoralens; Fries rearrangements. Furocoumarins; furocoumarin analogs; psoralens; Fries rearrangements.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Traven, V.F. New Synthetic Routes to Furocoumarins and Their Analogs: A Review. Molecules 2004, 9, 50-66.

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