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Molecules 2003, 8(9), 678-686; doi:10.3390/80900678
Article

Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one

Received: 7 March 2003; in revised form: 24 July 2003 / Accepted: 3 August 2003 / Published: 17 August 2003
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Abstract: 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c][1,5]thiazepin-3(2H)-one, a key intermediate in the synthesis of pyrrolopyridothiazepine derivatives, was synthesized from bis(4H-pyrrolo-3-pyridyl)disulfide and α-bromo-(4-methoxyphenyl) acetic acid ethyl ester in order to develop a novel calcium channel antagonist.
Keywords: Calcium channel antagonist; Thiation; Pyrrolopyridothiazepine; Intramolecular cyclization Calcium channel antagonist; Thiation; Pyrrolopyridothiazepine; Intramolecular cyclization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ma, E. Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one. Molecules 2003, 8, 678-686.

AMA Style

Ma E. Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one. Molecules. 2003; 8(9):678-686.

Chicago/Turabian Style

Ma, Eunsook. 2003. "Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one." Molecules 8, no. 9: 678-686.


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