Molecules 2003, 8(2), 263-268; doi:10.3390/80200263
Article

Synthesis of 2-(2-R1-Hydrazino)-5-(R2-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate

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Received: 12 July 2002; in revised form: 20 February 2003 / Accepted: 21 February 2003 / Published: 28 February 2003
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: 3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arenediazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d). Thiosemicarbazides 2a–d in the presence of bases selectively transform into 2-(2-R1-hydrazino)-5-(R2-benzyl)-2-thiazolines (3a–d).
Keywords: Arylation; allyl isothiocyanate; thiosemicarbazides; 2-thiazolines; cyclizations
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MDPI and ACS Style

Karpyak, V.V.; Obushak, M.D.; Ganushchak, M.I. Synthesis of 2-(2-R1-Hydrazino)-5-(R2-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate. Molecules 2003, 8, 263-268.

AMA Style

Karpyak VV, Obushak MD, Ganushchak MI. Synthesis of 2-(2-R1-Hydrazino)-5-(R2-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate. Molecules. 2003; 8(2):263-268.

Chicago/Turabian Style

Karpyak, Volodymyr V.; Obushak, Mykola D.; Ganushchak, Mykola I. 2003. "Synthesis of 2-(2-R1-Hydrazino)-5-(R2-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate." Molecules 8, no. 2: 263-268.


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