2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents

doi:10.3390/81200910

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Molecules 2003, 8(12), 910-923; doi:10.3390/81200910

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2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents

Khadijah M. Al-Zaydi^1,* , Rita M. Borik¹ and Mohamed H. Elnagdi²

¹ Department of Chemistry, Girls College of Education, Jeddah, P.O. Box 50918, Jeddah 21533, Kingdom of Saudi Arabia ² Department of Chemistry, Faculty of Science, Cairo University, Giza, A.R. Egypt

* Author to whom correspondence should be addressed.

Received: 25 July 2003; in revised form: 22 December 2003 / Accepted: 23 December 2003 / Published: 31 December 2003

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Abstract: Utilization of 2-arylhydrazonopropanals for the synthesis of 2-arylhydrazonoimino propanones, 1,2,4-trizolo[4,3-a]pyrimidines, pyridopyridazine hydrazones, 3-oxaloalkanonitriles and 1,2,3-trizole derivatives by conventional heating and under microwave irradiation is described. Structural assignments are based on spectroscopic data and confirmed in some cases by X-ray crystallography.

Keywords: 2-Arylhydrazonopropanals; heterocyclic amines; active methylene compounds; microwave irradiation; X-ray structures

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MDPI and ACS Style

Al-Zaydi, K.M.; Borik, R.M.; Elnagdi, M.H. 2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents. Molecules 2003, 8, 910-923.

AMA Style

Al-Zaydi KM, Borik RM, Elnagdi MH. 2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents. Molecules. 2003; 8(12):910-923.

Chicago/Turabian Style

Al-Zaydi, Khadijah M.; Borik, Rita M.; Elnagdi, Mohamed H. 2003. "2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents." Molecules 8, no. 12: 910-923.

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