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Molecules 2003, 8(12), 910-923; doi:10.3390/81200910
Article

2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents

1,* , 1 and 2
1 Department of Chemistry, GirlÂ’s College of Education, Jeddah, P.O. Box 50918, Jeddah 21533, Kingdom of Saudi Arabia 2 Department of Chemistry, Faculty of Science, Cairo University, Giza, A.R. Egypt
* Author to whom correspondence should be addressed.
Received: 25 July 2003 / Revised: 22 December 2003 / Accepted: 23 December 2003 / Published: 31 December 2003
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Abstract

Utilization of 2-arylhydrazonopropanals for the synthesis of 2-arylhydrazonoimino propanones, 1,2,4-trizolo[4,3-a]pyrimidines, pyridopyridazine hydrazones, 3-oxaloalkanonitriles and 1,2,3-trizole derivatives by conventional heating and under microwave irradiation is described. Structural assignments are based on spectroscopic data and confirmed in some cases by X-ray crystallography.
Keywords: 2-Arylhydrazonopropanals; heterocyclic amines; active methylene compounds; microwave irradiation; X-ray structures 2-Arylhydrazonopropanals; heterocyclic amines; active methylene compounds; microwave irradiation; X-ray structures
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Al-Zaydi, K.M.; Borik, R.M.; Elnagdi, M.H. 2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents. Molecules 2003, 8, 910-923.

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