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Molecules 2003, 8(12), 910-923; doi:10.3390/81200910
Article

2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents

1,* , 1 and 2
Received: 25 July 2003 / Revised: 22 December 2003 / Accepted: 23 December 2003 / Published: 31 December 2003
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Abstract

Utilization of 2-arylhydrazonopropanals for the synthesis of 2-arylhydrazonoimino propanones, 1,2,4-trizolo[4,3-a]pyrimidines, pyridopyridazine hydrazones, 3-oxaloalkanonitriles and 1,2,3-trizole derivatives by conventional heating and under microwave irradiation is described. Structural assignments are based on spectroscopic data and confirmed in some cases by X-ray crystallography.
Keywords: 2-Arylhydrazonopropanals; heterocyclic amines; active methylene compounds; microwave irradiation; X-ray structures 2-Arylhydrazonopropanals; heterocyclic amines; active methylene compounds; microwave irradiation; X-ray structures
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Al-Zaydi, K.M.; Borik, R.M.; Elnagdi, M.H. 2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents. Molecules 2003, 8, 910-923.

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