Molecules 2002, 7(7), 507-510; doi:10.3390/70700507
Article

Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane

R. Chioua 1,* email, F. Benabdelouahab 1 , M. Chioua 2 , R. Martínez-Alvarez 2  and A. Herrera Fernández 2 email
1 Département de Chimie, Université Abdelmalek Essaâdi, Faculté des Sciences, B.P 2121, Tétouan, Morocco 2 Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense, E- 28040, Spain
* Author to whom correspondence should be addressed.
Received: 24 September 2001; in revised form: 3 July 2002 / Accepted: 8 July 2002 / Published: 31 July 2002
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Abstract: The [4+2] cycloaddition between 2,4-diphenylpyrimidine ortho-quinodimethane and dimethyl acetylenedicarboxylate leads to 2,4-diphenylquinazoline-6,7-dicarboxylate (6). 2,4-Diphenylfuro[3,4-g]quinazoline-6,8-dione (7) is also obtained by basic hydrolysis of compound 6, followed by the closure of the resulting diacid in acetic anhydride.
Keywords: [4+2] Cycloaddition; Diels-Alder adduct; dimethyl 2; 4-diphenylquinazoline dicarboxylate

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MDPI and ACS Style

Chioua, R.; Benabdelouahab, F.; Chioua, M.; Martínez-Alvarez, R.; Fernández, A.H. Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane. Molecules 2002, 7, 507-510.

AMA Style

Chioua R, Benabdelouahab F, Chioua M, Martínez-Alvarez R, Fernández AH. Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane. Molecules. 2002; 7(7):507-510.

Chicago/Turabian Style

Chioua, R.; Benabdelouahab, F.; Chioua, M.; Martínez-Alvarez, R.; Fernández, A. H. 2002. "Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane." Molecules 7, no. 7: 507-510.

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