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Molecules 2002, 7(1), 38-50; doi:10.3390/70100038
Article

Thirteen New Xanthone Derivatives from Calophyllum caledonicum (Clusiaceae)

1, 1, 2, 2, 1, 1 and 1,*
1 SONAS, UFR des Sciences Pharmaceutiques et Ingénierie de la santé, 16 Bd Daviers, F-49100 Angers, France 2 ICSN-CNRS, Gif-sur-Yvette, F-91191, France
* Author to whom correspondence should be addressed.
Received: 11 October 2001 / Revised: 28 November 2001 / Accepted: 28 November 2001 / Published: 31 January 2002
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Abstract

An EtOAc extract of the stem bark of Calophyllum caledonicum (Clusiaceae) yielded thirteen new hydroxylated and/or prenylated xanthone derivatives, namely 5-hydroxy-8-methoxyxanthone (1), 3,5-dihydroxy-1,2-dimethoxyxanthone (2), 1,8-dihydroxy-6,7-dimethoxyxanthone (3), 5,7-dihydroxy-2,6-dimethoxyxanthone (4), 6,8-dihydroxy-3,7-dimethoxy-xanthone (5), 2,5,6,7,8-pentahydroxyxanthone (6), 1,3,8-trihydroxy-5,7-dimethoxyxanthone (7) and according to a previously adopted nomenclature [3], caledonixanthone G-L. (8-13). The structural elucidation of 1-13 were mainly established on the basis of 1D and 2D NMR and HRMS spectroscopic analysis.
Keywords: NMR; MS; xanthones; Calophyllum caledonicum; Guttiferae NMR; MS; xanthones; Calophyllum caledonicum; Guttiferae
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Morel, C.; Hay, A.-E.; Litaudon, M.; Sévenet, T.; Séraphin, D.; Bruneton, J.; Richomme, P. Thirteen New Xanthone Derivatives from Calophyllum caledonicum (Clusiaceae). Molecules 2002, 7, 38-50.

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