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(1S,6S)-Tetrazolo [1,5-g]-7-Aza-trans-himachal-2-ene
 
 
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(1S,2S,3R,6R,7R)-Epoxy-himachal-7-ol

Laboratoire de Chimie des Substances Naturelles et des Hétérocycles, Département de Chimie, Faculté des Sciences-SemLalia, B.P. 2390, 40001 Marrakech, Maroc
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Author to whom correspondence should be addressed.
Molecules 2001, 6(6), M228; https://doi.org/10.3390/M228
Submission received: 12 February 2001 / Accepted: 15 May 2001 / Published: 25 May 2001
(This article belongs to the Section Molbank Section of Molecules, 1997-2001)
Molecules 06 m228 i001
To a mixture of lithium aluminium hydride (0,16 g, 4 mmol) in dry ether (50 mL) [1] was added a solution of (10 mL) of epoxide 1 [1,2] (1 g, 4 mmol) in dry ether dropwise at room temperature. After stirring for 24 hours, the mixture is hydrolysed with 5 mL of water, filtered and extracted with ether. The combined extracts were dried with Na2SO4, concentrated and purified by chromatography on silica gel column using hexane/chloroform: 8/2 as solvent to give 2 (100 %).
MS (EI, 70eV): 238 (M+.).
1H NMR (400 MHz, CCl4): 0.88 (s,C14-H3), 1.05(s,C15-H3); 1.15 (s, C12-H3); 1.32 (s, C13-H3); 2.97 (s,C2-H).
13C NMR (100 MHz, CCl4): 46.25 (C1), 63.91 (C2), 56.94 (C3), 38.75 (C4), 35 (C5), 45 (C6), 73.38 (C7), 40 (C8), 35.1 (C9),30 (C10), 41.25 (C11), 25 (C12), 31.25 (C13), 22.5 (C14), 21.25 (C15).

Supplementary Materials

References

  1. Kiyomi, K.; Ippei, N.; Fumiyuki, M.; Morio, N.; Mikihiro, O.; Yochito, T.; Hideo, K. J. Org. Chem. 1995, 60, 3318–3333.
  2. Lassaba, E.; Eljamili, H.; Chekroun, A.; Benharref, A.; Chiarooni, A.; Riche C.; Lavergne, J.-P. Syn Comm. 1998, 28, 2641–2651.
  3. Chiaroni, A.; Riche, C.; Benharref, A.; Chekroun, A.; Lavergne, J.-P. Acta Cryst. 1992, C48, 1720.
Sample Availability: Available from the authors and from MDPI.

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MDPI and ACS Style

Dakir, M.; Lassaba, E.; Chekroun, A.; Benharref, A. (1S,2S,3R,6R,7R)-Epoxy-himachal-7-ol. Molecules 2001, 6, M228. https://doi.org/10.3390/M228

AMA Style

Dakir M, Lassaba E, Chekroun A, Benharref A. (1S,2S,3R,6R,7R)-Epoxy-himachal-7-ol. Molecules. 2001; 6(6):M228. https://doi.org/10.3390/M228

Chicago/Turabian Style

Dakir, M., E. Lassaba, A. Chekroun, and A. Benharref. 2001. "(1S,2S,3R,6R,7R)-Epoxy-himachal-7-ol" Molecules 6, no. 6: M228. https://doi.org/10.3390/M228

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