Tricarbonyl(h6-Arene)Chromium(0) Complexes as Chiral Auxiliaries: Asymmetric Synthesis of b-Lactones

doi:10.3390/60100013

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Molecules 2001, 6(1), 13-20; doi:10.3390/60100013

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Tricarbonyl(h6-Arene)Chromium(0) Complexes as Chiral Auxiliaries: Asymmetric Synthesis of b-Lactones

Paola D. Buttero * and Deborah Montrasio

Dipartimento di Chimica Organica e Industriale dell’Universita’ di Milano e Centro CNR, Via Venezian, 21-20133 Milano Italy

* Author to whom correspondence should be addressed.

Received: 24 July 2000; in revised form: 18 December 2000 / Accepted: 18 December 2000 / Published: 16 January 2001

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Abstract: The optically pure tricarbonyl(h⁶-2-substituted benzaldehydes)chromium are used as chiral auxiliaries in the condensation with a series of doubly lithiated carboxylic acids. The intramolecular ring closure of the obtained Cr(CO)₃ complexed b-hydroxyacids affords the optically pure b-lactones in satisfactory yield.

Keywords: b-lactones; stereoselective synthesis; 2-oxetanones; chromiumtricarbonyl benzaldehydes

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MDPI and ACS Style

Buttero, P.D.; Montrasio, D. Tricarbonyl(h6-Arene)Chromium(0) Complexes as Chiral Auxiliaries: Asymmetric Synthesis of b-Lactones. Molecules 2001, 6, 13-20.

AMA Style

Buttero P.D., Montrasio D. Tricarbonyl(h6-Arene)Chromium(0) Complexes as Chiral Auxiliaries: Asymmetric Synthesis of b-Lactones. Molecules. 2001; 6(1):13-20.

Chicago/Turabian Style

Buttero, Paola D.; Montrasio, Deborah. 2001. "Tricarbonyl(h6-Arene)Chromium(0) Complexes as Chiral Auxiliaries: Asymmetric Synthesis of b-Lactones." Molecules 6, no. 1: 13-20.

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