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Molecules 2000, 5(3), 580-582; doi:10.3390/50300580

The Importance of Keto-Enol Forms of Arylpropanoids Acting as Antifungal Compounds

1, 1, 1, 1, 1, 1, 2 and 2
1 Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Cátedra de Química General. Chacabuco y Pedernera. 5700 San Luis, Argentina 2 Universidad Nacional de Rosario. Facultad de Bioquímica y Farmacia. Cátedra de Farmacognosia. Rosario, Argentina
* Author to whom correspondence should be addressed.
Published: 22 March 2000
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We report here the importance of a keto-enol equilibrium of an arylpropanoid series acting as antifungal agents. An interesting relationship between ln MIC, ∆E enolization and net atomic charges was found. Two compounds were synthesized and their MIC evaluated in order to prove the above relationship.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Giannini, F.; Devia, C.; Rodríguez, A.; Enriz, R.; Suvire, F.; Baldoni, H.; Furlan, R.; Zacchino, S. The Importance of Keto-Enol Forms of Arylpropanoids Acting as Antifungal Compounds. Molecules 2000, 5, 580-582.

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