3,3-Dimethylacylthioureas: "S", "-S", "U" or "W" Conformation?

doi:10.3390/50300445

This article is

freely available
re-usable

Molecules 2000, 5(3), 445-446; doi:10.3390/50300445

Article

3,3-Dimethylacylthioureas: "S", "-S", "U" or "W" Conformation?

M. Sosa¹, M. Piris² and G. Burton³

¹ Facultad de Química, Universidad de La Habana, Cuba ² Instituto Superior de Ciencias y Tecnologías Nucleares, Cuba ³ Depto. de Química Orgánica, Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires, Argentina

* Author to whom correspondence should be addressed.

Published: 22 March 2000

Download PDF Full-Text [15 KB, uploaded 21 November 2008 13:21 CET]

Abstract: We report a study of 3,3-dimethyl substituted acylthioureas. X ray data and quantum mechanical calculations demonstrated that the "S" conformation is the most stable both for the acylthioureas and the corresponding anions. The high regioselectivity towards S-alkylation is explained on the basis of the localization of the HOMO mainly over the sulfur atom.

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Sosa, M.; Piris, M.; Burton, G. 3,3-Dimethylacylthioureas: "S", "-S", "U" or "W" Conformation? Molecules 2000, 5, 445-446.

AMA Style

Sosa M, Piris M, Burton G. 3,3-Dimethylacylthioureas: "S", "-S", "U" or "W" Conformation? Molecules. 2000; 5(3):445-446.

Chicago/Turabian Style

Sosa, M.; Piris, M.; Burton, G. 2000. "3,3-Dimethylacylthioureas: "S", "-S", "U" or "W" Conformation?" Molecules 5, no. 3: 445-446.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert