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Molecules 2000, 5(2), 99-113; doi:10.3390/50200099

Novel Coumarin Derivatives with Expected Biological Activity

* ,  and
Therapeutical Chemistry Department, National Research Centre, Dokki, Cairo, Egypt
* Author to whom correspondence should be addressed.
Received: 13 August 1999 / Accepted: 20 October 1999 / Published: 16 February 2000
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A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
Keywords: Substituted coumarins; nitro reduction; benzylidinyl amino coumarins Substituted coumarins; nitro reduction; benzylidinyl amino coumarins
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nofal, Z.M.; El-Zahar, M.I.; Abd El-Karim, S.S. Novel Coumarin Derivatives with Expected Biological Activity. Molecules 2000, 5, 99-113.

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