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Molecules 2000, 5(2), 99-113; doi:10.3390/50200099
Article

Novel Coumarin Derivatives with Expected Biological Activity

* ,  and
Therapeutical Chemistry Department, National Research Centre, Dokki, Cairo, Egypt
* Author to whom correspondence should be addressed.
Received: 13 August 1999 / Accepted: 20 October 1999 / Published: 16 February 2000
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Abstract

A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
Keywords: Substituted coumarins; nitro reduction; benzylidinyl amino coumarins Substituted coumarins; nitro reduction; benzylidinyl amino coumarins
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Nofal, Z.M.; El-Zahar, M.I.; Abd El-Karim, S.S. Novel Coumarin Derivatives with Expected Biological Activity. Molecules 2000, 5, 99-113.

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