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Molecules 1999, 4(11), 329-332; doi:10.3390/41100329
Article

8-Chloro-11-[4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazino]-5H-dibenzo[b,e][1,4]diazepine

Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University (Parkville Campus), 381 Royal Parade, Parkville, Victoria, 3052, Australia
Received: 13 August 1999 / Accepted: 20 October 1999 / Published: 25 October 1999
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Abstract

A method to synthesize desmethylclozapine, 3, is reported. The procedure afforded the target compound in 69% yield. A by-product, isolated from the reaction mixture in 11% yield, proved to be the title compound, 4.
Keywords: desmethylclozapine; amidine formation; titanium tetrachloride desmethylclozapine; amidine formation; titanium tetrachloride
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Capuano, B. 8-Chloro-11-[4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazino]-5H-dibenzo[b,e][1,4]diazepine. Molecules 1999, 4, 329-332.

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