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Molecules 1999, 4(1), 13-15; doi:10.3390/40100013
Article

An Efficient, Self-Protecting Route to Dimethyl 4-Amino-4-[2-(methoxycarbonyl)ethyl]-heptanedioate HCl

 and *
Department of Chemistry and Biochemistry, South Dakota State University, Box 2202, Brookings, South Dakota 57007, USA
* Author to whom correspondence should be addressed.
Received: 10 September 1998 / Accepted: 5 January 1999 / Published: 9 February 1999
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Abstract

A method to reduce the nitro moiety in dimethyl 4-nitro-4-[1-[2(methoxycarbonyl)ethyl]]heptanedioate using a T-1 Raney nickel catalyst in an acidic environment is reported. The method avoids facile lactam formation.
Keywords: Nitro reduction; lactam formation; amine salt Nitro reduction; lactam formation; amine salt
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Henrie, S.; Majerle, R.S.K. An Efficient, Self-Protecting Route to Dimethyl 4-Amino-4-[2-(methoxycarbonyl)ethyl]-heptanedioate HCl. Molecules 1999, 4, 13-15.

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