Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles

doi:10.3390/30600149

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Molecules 1998, 3(6), 149-158; doi:10.3390/30600149

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Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles

Margita Lacova ¹^,* , Dusan Loos ¹, Mikulas Furdik ¹, Maria Matulova ² and Hafez M. El-Shaaer ³

¹ Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, SK-84215 Bratislava, Slovak Republic ² Slovak Academy of Sciences, 842 38 Bratislava, Slovak Republic ³ Department of Chemistry, Faculty of Education,Ain Shams University, Roxy, Cairo, Egypt

* Author to whom correspondence should be addressed.

Received: 27 January 1998 / Accepted: 14 April 1998 / Published: 15 May 1998

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Abstract: The synthesis of eight hydroxy- and 2-oxopyranochromone-3-carboxaldehydes 3, 5 and their reactions with 2-hydroxyaniline, 2,4-dinitrophenylhydrazine and 2-benzothiazolylhydrazine were investigated. Products were confirmed by IR, NMR spectral and elemental analysis data. The semi-empirical AM1 quantum-chemical method has been used to study optimal geometries and heats of formation of synthesized 3-formylchromones.

Keywords: 3-Formylchromones; Vilsmeier - Haack reaction; 2-oxobenzopyrane; imines; enamines; AM1 calculations

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MDPI and ACS Style

Lacova, M.; Loos, D.; Furdik, M.; Matulova, M.; El-Shaaer, H.M. Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles. Molecules 1998, 3, 149-158.

AMA Style

Lacova M., Loos D., Furdik M., Matulova M., El-Shaaer H.M. Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles. Molecules. 1998; 3(6):149-158.

Chicago/Turabian Style

Lacova, Margita; Loos, Dusan; Furdik, Mikulas; Matulova, Maria; El-Shaaer, Hafez M. 1998. "Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles." Molecules 3, no. 6: 149-158.

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