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Molecules 2018, 23(8), 1870; https://doi.org/10.3390/molecules23081870

Ultrasensitive (Co)polymers Based on Poly(methacrylamide) Structure with Fining-Tunable pH Responsive Value

1
Shandong Provincial Key Laboratory of Oilfield Chemistry, School of Petroleum Engineering, China University of Petroleum (East China), Qingdao 266580, China
2
Department of Chemistry, Capital Normal University, 105 West 3rd Ring North Rd, Beijing 100048, China
*
Author to whom correspondence should be addressed.
Academic Editors: Jianxun Ding, Yang Li and Mingqiang Li
Received: 25 June 2018 / Revised: 12 July 2018 / Accepted: 15 July 2018 / Published: 27 July 2018
(This article belongs to the Special Issue Smart and Functional Polymers)
Full-Text   |   PDF [1911 KB, uploaded 27 July 2018]   |  

Abstract

Novel pH responsive copolymers with tertiary amine groups were prepared by free radical polymerization with 2-(dialkylamino)ethyl methacrylate monomers. These polymers were pH sensitive with the ability to be responsively fine-tuned in aqueous solution, which was proven through titration, transmittance measurements, and proton nuclear magnetic resonance spectroscopy. The polymers were soluble in water at low pH values, induced by electrostatic repulsion between amine groups, and aggregated above their pKa value due to the hydrophobic effect of the alkyls. The pH responsive values were precisely tuned from 7.4 to 4.8 by increasing the hydrophobic monomer ratio. Our work provides a novel approach for the development of ultrasensitive pH-responsive polymers for application in biomedical materials. View Full-Text
Keywords: fine-tuning; pH responsive; poly(methacrylamide)s; phase transition fine-tuning; pH responsive; poly(methacrylamide)s; phase transition
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Fan, H.; Li, P.; Li, W.; Li, H.; Huang, X. Ultrasensitive (Co)polymers Based on Poly(methacrylamide) Structure with Fining-Tunable pH Responsive Value. Molecules 2018, 23, 1870.

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