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Molecules 2018, 23(6), 1484;

A Review of the Extraction and Determination Methods of Thirteen Essential Vitamins to the Human Body: An Update from 2010

Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Graduate School of Peking Union Medical College, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100032, China
School of Pharmacy, China Medical University, Shenyang 110013, China
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 11 May 2018 / Revised: 12 June 2018 / Accepted: 17 June 2018 / Published: 19 June 2018
(This article belongs to the Special Issue Modern Sample Preparation Approaches for Separation Science)
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Vitamins are a class of essential nutrients in the body; thus, they play important roles in human health. The chemicals are involved in many physiological functions and both their lack and excess can put health at risk. Therefore, the establishment of methods for monitoring vitamin concentrations in different matrices is necessary. In this review, an updated overview of the main pretreatments and determination methods that have been used since 2010 is given. Ultrasonic assisted extraction, liquid–liquid extraction, solid phase extraction and dispersive liquid–liquid microextraction are the most common pretreatment methods, while the determination methods involve chromatography methods, electrophoretic methods, microbiological assays, immunoassays, biosensors and several other methods. Different pretreatments and determination methods are discussed. View Full-Text
Keywords: vitamins; extraction; determination; review vitamins; extraction; determination; review

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Zhang, Y.; Zhou, W.-E.; Yan, J.-Q.; Liu, M.; Zhou, Y.; Shen, X.; Ma, Y.-L.; Feng, X.-S.; Yang, J.; Li, G.-H. A Review of the Extraction and Determination Methods of Thirteen Essential Vitamins to the Human Body: An Update from 2010. Molecules 2018, 23, 1484.

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