Next Article in Journal
Evaluating Molecular Properties Involved in Transport of Small Molecules in Stratum Corneum: A Quantitative Structure-Activity Relationship for Skin Permeability
Next Article in Special Issue
The Chemical Composition and Metabolic Effects of Attalea phalerata Nut Oil in Hyperlipidemic Rats Induced by a High-Fructose Diet
Previous Article in Journal
Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats
Previous Article in Special Issue
UFLC-Q-TOF-MS/MS-Based Screening and Identification of Flavonoids and Derived Metabolites in Human Urine after Oral Administration of Exocarpium Citri Grandis Extract
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessReview
Molecules 2018, 23(4), 910; https://doi.org/10.3390/molecules23040910

Stryphnodendron Species Known as “Barbatimão”: A Comprehensive Report

1
Department of Drugs and Medicines, School of Pharmaceutical Sciences, Sao Paulo State University-UNESP, Rodovia Araraquara-Jaú, km 1, Araraquara 14800-903, Sao Paulo, Brazil
2
Pró Reitoria de Pesquisa e Pós-graduação, Universidade do Sagrado Coração, Bauru 17011-160, São Paulo, Brazil
*
Author to whom correspondence should be addressed.
Received: 1 December 2017 / Revised: 26 January 2018 / Accepted: 31 January 2018 / Published: 15 April 2018
View Full-Text   |   Download PDF [924 KB, uploaded 15 April 2018]   |  

Abstract

Stryphnodendron spp., popularly known as “barbatimão”, is the native Brazilian tree most often employed to treat wounds and infections. The aim of the present study was to highlight the importance of S. adstringens, as well as other Stryphnodendron species recognized as “barbatimão”, to human health, depicting the relevance of ethnopharmacological knowledge to scientific evidence for uses, related chemical compounds, development of pharmaceutical formulations, and the establishment of toxicity parameters. For this purpose, the literature databases PubMed, Scielo, Lilacs, CAPES Thesis and Google Scholar were searched until 2017. It was observed that stem bark was the primary part of the plant used, mainly as a decoction, for wound healing and treatment of infectious and inflammatory disorders. Confirmed biological activities, including wound healing, anti-inflammatory, antioxidant, and antimicrobial activities, were related to the presence of compounds from tannin class, mostly proanthocyanidins. Toxicity parameters for stem bark were inconclusive, but toxicity was observed to a significant extent when seeds were ingested by cattle or other animals. Due to these important and confirmed biological activities, government policy encourages the phytotherapic use of S. adstringens, and some formulations with stem bark extracts were developed and patented. Furthermore, antiprotozoal, hypoglycemic and antiviral activities were identified as promising. View Full-Text
Keywords: ethnopharmacology; medicinal plant; biological activity; tannin; catechin; wound healing ethnopharmacology; medicinal plant; biological activity; tannin; catechin; wound healing
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Souza-Moreira, T.M.; Queiroz-Fernandes, G.M.; Pietro, R.C.L.R. Stryphnodendron Species Known as “Barbatimão”: A Comprehensive Report. Molecules 2018, 23, 910.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top