Melatonin and Cancer Hallmarks
AbstractMelatonin is a natural indoleamine produced by the pineal gland that has many functions, including regulation of the circadian rhythm. Many studies have reported the anticancer effect of melatonin against a myriad of cancer types. Cancer hallmarks include sustained proliferation, evading growth suppressors, metastasis, replicative immortality, angiogenesis, resisting cell death, altered cellular energetics, and immune evasion. Melatonin anticancer activity is mediated by interfering with various cancer hallmarks. This review summarizes the anticancer role of melatonin in each cancer hallmark. The studies discussed in this review should serve as a solid foundation for researchers and physicians to support basic and clinical studies on melatonin as a promising anticancer agent. View Full-Text
Share & Cite This Article
Talib, W.H. Melatonin and Cancer Hallmarks. Molecules 2018, 23, 518.
Talib WH. Melatonin and Cancer Hallmarks. Molecules. 2018; 23(3):518.Chicago/Turabian Style
Talib, Wamidh H. 2018. "Melatonin and Cancer Hallmarks." Molecules 23, no. 3: 518.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.