Next Article in Journal
Quantitative Analysis, Extraction Optimization, and Biological Evaluation of Cudrania tricuspidata Leaf and Fruit Extracts
Next Article in Special Issue
The Influence of Accelerated UV-A and Q-SUN Irradiation on the Antimicrobial Properties of Coatings Containing ZnO Nanoparticles
Previous Article in Journal
Topological Characterization of Carbon Graphite and Crystal Cubic Carbon Structures
Previous Article in Special Issue
Biosynthesis of Silver Nanoparticles on Orthodontic Elastomeric Modules: Evaluation of Mechanical and Antibacterial Properties
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Molecules 2017, 22(9), 1487; doi:10.3390/molecules22091487

Silver Oxide Coatings with High Silver-Ion Elution Rates and Characterization of Bactericidal Activity

1
Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08028, USA
2
Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA
3
Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA
4
Department of Electrical and Computer Engineering, Rowan University, Glassboro, NJ 08028, USA
5
Department of Molecular Biology, Rowan University, Stratford, NJ 08084, USA
6
Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 7 August 2017 / Revised: 29 August 2017 / Accepted: 30 August 2017 / Published: 7 September 2017
(This article belongs to the Special Issue Antibacterial Materials and Coatings)
View Full-Text   |   Download PDF [4495 KB, uploaded 7 September 2017]   |  

Abstract

This paper reports the synthesis and characterization of silver oxide films for use as bactericidal coatings. Synthesis parameters, dissolution/elution rate, and bactericidal efficacy are reported. Synthesis conditions were developed to create AgO, Ag2O, or mixtures of AgO and Ag2O on surfaces by reactive magnetron sputtering. The coatings demonstrate strong adhesion to many substrate materials and impede the growth of all bacterial strains tested. The coatings are effective in killing Escherichia coli and Staphylococcus aureus, demonstrating a clear zone-of-inhibition against bacteria growing on solid media and the ability to rapidly inhibit bacterial growth in planktonic culture. Additionally, the coatings exhibit very high elution of silver ions under conditions that mimic dynamic fluid flow ranging between 0.003 and 0.07 ppm/min depending on the media conditions. The elution of silver ions from the AgO/Ag2O surfaces was directly impacted by the complexity of the elution media, with a reduction in elution rate when examined in complex cell culture media. Both E. coli and S. aureus were shown to bind ~1 ppm Ag+/mL culture. The elution of Ag+ resulted in no increases in mammalian cell apoptosis after 24 h exposure compared to control, but apoptotic cells increased to ~35% by 48 and 72 h of exposure. Taken together, the AgO/Ag2O coatings described are effective in eliciting antibacterial activity and have potential for application on a wide variety of surfaces and devices. View Full-Text
Keywords: bactericidal coatings; antibacterial; silver oxide; reactive sputtering; thin film coatings bactericidal coatings; antibacterial; silver oxide; reactive sputtering; thin film coatings
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Goderecci, S.S.; Kaiser, E.; Yanakas, M.; Norris, Z.; Scaturro, J.; Oszust, R.; Medina, C.D.; Waechter, F.; Heon, M.; Krchnavek, R.R.; Yu, L.; Lofland, S.E.; Demarest, R.M.; Caputo, G.A.; Hettinger, J.D. Silver Oxide Coatings with High Silver-Ion Elution Rates and Characterization of Bactericidal Activity. Molecules 2017, 22, 1487.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top