Looking Back, Looking Forward at Halogen Bonding in Drug Discovery
AbstractHalogen bonding has emerged at the forefront of advances in improving ligand: receptor interactions. In particular the newfound ability of this extant non-covalent-bonding phenomena has revolutionized computational approaches to drug discovery while simultaneously reenergizing synthetic approaches to the field. Here we survey, via examples of classical applications involving halogen atoms in pharmaceutical compounds and their biological hosts, the unique advantages that halogen atoms offer as both Lewis acids and Lewis bases. View Full-Text
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Mendez, L.; Henriquez, G.; Sirimulla, S.; Narayan, M. Looking Back, Looking Forward at Halogen Bonding in Drug Discovery. Molecules 2017, 22, 1397.
Mendez L, Henriquez G, Sirimulla S, Narayan M. Looking Back, Looking Forward at Halogen Bonding in Drug Discovery. Molecules. 2017; 22(9):1397.Chicago/Turabian Style
Mendez, Lois; Henriquez, Gabriela; Sirimulla, Suman; Narayan, Mahesh. 2017. "Looking Back, Looking Forward at Halogen Bonding in Drug Discovery." Molecules 22, no. 9: 1397.
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