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Molecules 2017, 22(8), 1383; doi:10.3390/molecules22081383

The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities

School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China
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Received: 19 July 2017 / Accepted: 16 August 2017 / Published: 21 August 2017
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Abstract

The genus Alnus (Betulaceae) is comprised of more than 40 species. Many species of this genus have a long history of use in folk medicines. Phytochemical investigations have revealed the presence of diarylheptanoids, polyphenols, flavonoids, terpenoids, steroids and other compounds. Diarylheptanoids, natural products with a 1,7-diphenylheptane structural skeleton, are the dominant constituents in the genus, whose anticancer effect has been brought into focus. Pure compounds and crude extracts from the genus exhibit a wide spectrum of pharmacological activities both in vitro and in vivo. This paper compiles 273 naturally occurring compounds from the genus Alnus along with their structures and pharmacological activities, as reported in 138 references. View Full-Text
Keywords: chemical constituents; biological activities; Alnus; diarylheptanoids chemical constituents; biological activities; Alnus; diarylheptanoids
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Ren, X.; He, T.; Chang, Y.; Zhao, Y.; Chen, X.; Bai, S.; Wang, L.; Shen, M.; She, G. The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities. Molecules 2017, 22, 1383.

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