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Molecules 2017, 22(8), 1370; doi:10.3390/molecules22081370

Metal-Based Nanoparticles for the Treatment of Infectious Diseases

Department of Chemistry, University of Fort Hare, Alice Campus, Eastern Cape 5700, South Africa
Received: 24 July 2017 / Accepted: 15 August 2017 / Published: 18 August 2017
(This article belongs to the Special Issue Metal Based Drugs: Opportunities and Challenges)
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Abstract

Infectious diseases can be transmitted and they cause a significant burden on public health globally. They are the greatest world killers and it is estimated that they are responsible for the demise of over 17 million people annually. The impact of these diseases is greater in the developing countries. People with compromised immune systems and children are the most affected. Infectious diseases may be caused by bacteria, viruses, and protozoa. The treatment of infectious diseases is hampered by simultaneous resistance to multiple drugs, indicating that there is a serious and pressing need to develop new therapeutics that can overcome drug resistance. This review will focus on the recent reports of metal-based nanoparticles that are potential therapeutics for the treatment of infectious diseases and their biological efficacy (in vitro and in vivo). View Full-Text
Keywords: infectious diseases; metal-based therapeutics; influenza; HIV; herpes; malaria; cervical cancer; tuberculosis infectious diseases; metal-based therapeutics; influenza; HIV; herpes; malaria; cervical cancer; tuberculosis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Aderibigbe, B.A. Metal-Based Nanoparticles for the Treatment of Infectious Diseases. Molecules 2017, 22, 1370.

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