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Molecules 2017, 22(6), 873; doi:10.3390/molecules22060873

Impact of Maturity of Malay Cherry (Lepisanthes alata) Leaves on the Inhibitory Activity of Starch Hydrolases

1
Food Science and Technology Programme, c/o Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
2
National University of Singapore (Suzhou) Research Institute, 377 Lin Quan Street, Suzhou Industrial Park, Suzhou 215123, Jiangsu, China
*
Author to whom correspondence should be addressed.
Academic Editor: Isabel Ferreira
Received: 24 April 2017 / Revised: 20 May 2017 / Accepted: 23 May 2017 / Published: 24 May 2017
(This article belongs to the Collection Bioactive Compounds)
View Full-Text   |   Download PDF [1837 KB, uploaded 26 May 2017]   |  

Abstract

Aqueous extracts of young (7-day-old) Malay cherry (Lepisanthes alata) leaves were incorporated into wheat and rice flours to evaluate their inhibitory activities against α-amylase and α-glucosidase. HPLC-ESI/MS2 results showed that the active components in young leaves were proanthocyanidins with lower mean degrees of polymerisation (≤10). The IC50 of the aqueous extracts of young leaves were 2.50 ± 0.03 and 12.91 ± 0.29 µg/mL, against α-amylase and α-glucosidase, which make them less active compared to the mature leaves. In contrast, total proanthocyanidins in aqueous extracts decreased as the leaves matured, indicating that the compounds in the mature leaves have much higher activity. However, there was no significant difference in the digestibility of wheat noodles incorporated with the aqueous extracts from either young or mature leaves. Interestingly, with regard to rice noodles, their digestibility was mostly reduced by incorporating aqueous extracts of young leaves compared to using mature leaves. View Full-Text
Keywords: Malay cherry leaves; wheat noodles; rice noodles; in vitro study; digestibility Malay cherry leaves; wheat noodles; rice noodles; in vitro study; digestibility
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Zhang, Y.; Gui, Y.; Huang, D. Impact of Maturity of Malay Cherry (Lepisanthes alata) Leaves on the Inhibitory Activity of Starch Hydrolases. Molecules 2017, 22, 873.

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