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Molecules 2017, 22(6), 855; doi:10.3390/molecules22060855

Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia

1
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
2
National Institutes for Food and Drug Control, Beijing 100050, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 31 March 2017 / Accepted: 17 May 2017 / Published: 23 May 2017
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Abstract

Two new phloroglucinols, lysidisides X and Y (1 and 2), and two known compounds, 2-(2-methylbutyryl)phloroglucinol 1-O-β-d-glucopyranoside (3) and (E)-resveratrol 3-(6″-galloyl)-O-β-d-glucopyranoside (4), have been isolated from the roots of Lysidice rhodostegia. The structures of 1 and 2 were elucidated primarily by NMR experiments. Their absolute configurations were deduced via circular dichroism (CD) data and electronic circular dichroism (ECD) calculations. Compounds 1 and 2 exhibited significant antioxidative activities with IC50 values of 12.0 and 11.8 µM, respectively. View Full-Text
Keywords: phloroglucinol; Lysidice rhodostegia; electronic circular dichroism (ECD) calculation; antioxidative activity phloroglucinol; Lysidice rhodostegia; electronic circular dichroism (ECD) calculation; antioxidative activity
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MDPI and ACS Style

Wu, X.-F.; Li, L.; Li, Y.; Lv, H.-N.; Liu, Y.-B.; Hu, Y.-C. Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia. Molecules 2017, 22, 855.

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