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Molecules 2017, 22(2), 297; doi:10.3390/molecules22020297

Adamantane in Drug Delivery Systems and Surface Recognition

1
University of Zagreb, Centre for Research and Knowledge Transfer in Biotechnology, Rockefellerova 10, 10000 Zagreb, Croatia
2
Department of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia
*
Author to whom correspondence should be addressed.
Academic Editor: Andrey A. Fokin
Received: 23 December 2016 / Revised: 19 January 2017 / Accepted: 11 February 2017 / Published: 16 February 2017
(This article belongs to the Special Issue Diamondoids and Their Derivatives)
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Abstract

The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application. View Full-Text
Keywords: adamantane; targeted drug delivery; liposomes; surface recognition; cyclodextrins; dendrimers adamantane; targeted drug delivery; liposomes; surface recognition; cyclodextrins; dendrimers
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MDPI and ACS Style

Štimac, A.; Šekutor, M.; Mlinarić-Majerski, K.; Frkanec, L.; Frkanec, R. Adamantane in Drug Delivery Systems and Surface Recognition. Molecules 2017, 22, 297.

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