Next Article in Journal
A DNA Barcode-Based RPA Assay (BAR-RPA) for Rapid Identification of the Dry Root of Ficus hirta (Wuzhimaotao)
Previous Article in Journal
Four New Compounds Obtained from Cultured Cells of Artemisia annua
Article Menu
Issue 12 (December) cover image

Export Article

Open AccessArticle
Molecules 2017, 22(12), 2250; doi:10.3390/molecules22122250

Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology

1
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
2
College of Public Administration, Nanjing Agricultural University, Nanjing 210095, China
3
Guelph Research and Development Centre, Agriculture & Agri-Food Canada, 93 Stone Road West, Guelph, ON N1G 5C9, Canada
*
Author to whom correspondence should be addressed.
Received: 7 November 2017 / Revised: 1 December 2017 / Accepted: 5 December 2017 / Published: 18 December 2017
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [4220 KB, uploaded 18 December 2017]   |  

Abstract

This work provides an optimized extraction approach intended to maximize the recovery of dihydromyricetin (DHM) from Chinese vine tea (Ampelopsis grossedentata) leaves. The presented work adopts a Box-Behnken design as a response surface methodology to understand the role and influence of specific extraction parameters including: time, temperature, and solvent composition/ethanol (%) on DHM final yields. Initially, single factor experiments were used to delineate the role of above factors (temperature, time, and solvent composition) before proceeding with three factors-three levels Box-Behnken design with 17 separate runs to assess the effect of multifactorial treatments on DHM recovery rates. The collected data shows that independent variables (solvent composition, time, and temperature) can significantly affect DHM recovery rates with maximum yields resulting from a combined 60 °C, 60% aqueous ethanol, and 180 min treatment. From the empirical point of view, the above optimized extraction protocol can substantially enhance processing and profitability margins with a minimum need of interventions or associated costs. View Full-Text
Keywords: dihydromyricetin; extraction; factors; temperature; solvent; time dihydromyricetin; extraction; factors; temperature; solvent; time
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Muhammad, U.; Lu, H.; Wang, J.; Han, J.; Zhu, X.; Lu, Z.; Tayyaba, S.; Hassan, Y.I. Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology. Molecules 2017, 22, 2250.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top