Bioactive Compounds from the Stems of Clausena lansium
AbstractIn view of the significant neuroprotective effect of Clausena lansium, we continued to separate the n-butanol and the water extracts from the stems of C. lansium in order to find the leading compounds with significant activity. Two new phenolic glycosides, Clausenolside A–B (1–2), one new pair of phenolic enantiomers (3a, 3b), and two new monoterpenoids, clausenapene A–B (4–5), together with twelve known analogues (6–17) were isolated from the stems of C. lansium. Compounds 1–17 were obtained from C. lansium for the first time. Compounds 3a, 3b, 4, 16, and 17 showed strong or moderate potential neuroprotective effects on inhibited PC12 cell injury induced by okadaic acid, and compound 9 exhibited strong potential hepatoprotective activities. Their structures were elucidated on the basis of spectroscopic analyses, including UV, IR, NMR experiments, and electronic circular dichroism (ECD) spectra. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Liu, J.; Li, C.-J.; Du, Y.-Q.; Li, L.; Sun, H.; Chen, N.-H.; Zhang, D.-M. Bioactive Compounds from the Stems of Clausena lansium. Molecules 2017, 22, 2226.
Liu J, Li C-J, Du Y-Q, Li L, Sun H, Chen N-H, Zhang D-M. Bioactive Compounds from the Stems of Clausena lansium. Molecules. 2017; 22(12):2226.Chicago/Turabian Style
Liu, Jie; Li, Chuang-Jun; Du, Yi-Qian; Li, Li; Sun, Hua; Chen, Nai-Hong; Zhang, Dong-Ming. 2017. "Bioactive Compounds from the Stems of Clausena lansium." Molecules 22, no. 12: 2226.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.