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Molecules 2017, 22(11), 1995; doi:10.3390/molecules22111995

Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides

Key Laboratory of Chinese Materia Medica, Ministry of Education of Heilongjiang University of Chinese Medicine, Harbin 150040, China
Heilongjiang Institute for Food and Drug Control, Harbin 150001, China
College of Pharmacy, Harbin University of Commerce, Harbin 150001, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Received: 28 October 2017 / Accepted: 15 November 2017 / Published: 22 November 2017
(This article belongs to the Section Natural Products)
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Four new compounds, aneglycoside A–C (13) and timosaponin U (4), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were determined through extensive spectroscopic analysis, chemical characteristics, and high-resolution mass spectrometry (HRMS). All the isolations were evaluated for cytotoxicity against HepG2, Hela, and SGC7901 human cancer lines. Compounds 1, 2, and 4 showed weak antiproliferative activities on HepG2, Hela, and SGC7901 cells. View Full-Text
Keywords: Asparagaceae; natural product; pyroglutamic acid; disaccharide; steroidal saponins; cytotoxicity Asparagaceae; natural product; pyroglutamic acid; disaccharide; steroidal saponins; cytotoxicity

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Yang, B.-Y.; Bi, X.-Y.; Liu, Y.; Li, G.-Y.; Yin, X.; Kuang, H.-X. Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides. Molecules 2017, 22, 1995.

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