Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study
AbstractLarix decidua bark is a waste of the timber industry and is widely diffused in Northern Italy. This material can be considered a good source of antioxidants and phytoconstituents with possible use in cosmetic or nutraceutical products. In this study, simple extraction of larch bark was performed using mixtures of ethanol/water. Furthermore, the phytochemical composition of larch bark extract was studied using LC-MSn methods and the main constituents were identified as flavonoids, spiro-polyphenols, and procyanidins. To confirm the identification by LC-MS semi-preparative HPLC was performed in order to isolate the main constituents and verify the structures by 1H-NMR. Antioxidant properties were studied using an in vitro approach combining DPPH assay and LC-MS in order to establish different roles of the various classes of phytochemicasl of the extract. DPPH activity of some of the isolated compounds was also assessed. The overall results indicate this waste material as a good source of antioxidant compounds, mainly procyanidins, whichresulted the most active constituents in the DPPH assay. View Full-Text
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Baldan, V.; Sut, S.; Faggian, M.; Dalla Gassa, E.; Ferrari, S.; De Nadai, G.; Francescato, S.; Baratto, G.; Dall’Acqua, S. Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study. Molecules 2017, 22, 1974.
Baldan V, Sut S, Faggian M, Dalla Gassa E, Ferrari S, De Nadai G, Francescato S, Baratto G, Dall’Acqua S. Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study. Molecules. 2017; 22(11):1974.Chicago/Turabian Style
Baldan, Valeria; Sut, Stefania; Faggian, Marta; Dalla Gassa, Elena; Ferrari, Sara; De Nadai, Gabriele; Francescato, Stefano; Baratto, Gianni; Dall’Acqua, Stefano. 2017. "Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study." Molecules 22, no. 11: 1974.
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