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Molecules 2017, 22(10), 1741; doi:10.3390/molecules22101741

A Highly Selective and Sensitive Fluorescent Turn-Off Probe for Cu2+ Based on a Guanidine Derivative

Department of Applied Chemistry, College of Science, Northeast Agricultural University, Harbin 150030, China
Author to whom correspondence should be addressed.
Received: 16 September 2017 / Accepted: 13 October 2017 / Published: 16 October 2017
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A new highly selective and sensitive fluorescent probe for Cu2+, N-n-butyl-4-(1′-cyclooctene-1′,3′,6′-triazole)-1,8-naphthalimide (L), was synthesized and evaluated. The structure of compound L was characterized via IR, 1H-NMR, 13C-NMR and HRMS. The fluorescent probe was quenched by Cu2+ with a 1:1 binding ratio and behaved as a “turn-off” sensor. An efficient and sensitive spectrofluorometric method was developed for detecting and estimating trace levels of Cu2+ in EtOH/H2O. The ligand exhibited excitation and emission maxima at 447 and 518 nm, respectively. The equilibrium binding constant of the ligand with Cu2+ was 1.57 × 104 M−1, as calculated using the Stern View Full-Text
Keywords: fluorescence; naphthalimide; guanidine; octatomic ring; copper ion fluorescence; naphthalimide; guanidine; octatomic ring; copper ion

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Ye, F.; Chai, Q.; Liang, X.-M.; Li, M.-Q.; Wang, Z.-Q.; Fu, Y. A Highly Selective and Sensitive Fluorescent Turn-Off Probe for Cu2+ Based on a Guanidine Derivative. Molecules 2017, 22, 1741.

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