Next Article in Journal
Pharmacokinetic Comparison of Scutellarin and Paeoniflorin in Sham-Operated and Middle Cerebral Artery Occlusion Ischemia and Reperfusion Injury Rats after Intravenous Administration of Xin-Shao Formula
Previous Article in Journal
Boronic Acid Group: A Cumbersome False Negative Case in the Process of Drug Design
Previous Article in Special Issue
Antioxidative and Antidiabetic Effects of Natural Polyphenols and Isoflavones
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessReview
Molecules 2016, 21(9), 1183; doi:10.3390/molecules21091183

A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease

1
Department of Physiology, Institute of Nutrition and Food Technology “Jose Mataix”, University of Granada, Biomedical Research Center, Avda. Conocimiento s.n., 18100 Armilla, Granada, Spain
2
Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy
3
Department of Stomalogy, Dental School, University of Sevilla, C/Avicena s.n., 41009 Sevilla, Andalusia, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 21 July 2016 / Revised: 25 August 2016 / Accepted: 31 August 2016 / Published: 7 September 2016
(This article belongs to the Special Issue 20th Anniversary of Molecules—Recent Advances in Natural Products)
View Full-Text   |   Download PDF [799 KB, uploaded 7 September 2016]   |  

Abstract

Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages health-promoting bacteria and maintenance of oral-hygiene. The role of nutrition in different chronic inflammatory diseases has been the subject of an increasing body of research in the last decades. In this sense, there has been an important increase in the volume of research on role of nutrition in periodontitis since the diet has known effects on the immune system and inflammatory cascades. Minerals play a key role in all these processes due to the multiple pathways where they participate. To clarify the role of the different minerals in the establishment, progression and/or treatment of this pathology, a systemically review of published literature cited in PubMed until May 2016 was conducted, which included research on the relationship of these elements with the onset and progression of periodontal disease. Among all the minerals, calcium dietary intake seems important to maintain alveolar bone. Likewise, dietary proportions of minerals that may influence its metabolism also can be relevant. Lastly, some observations suggest that all those minerals with roles in immune and/or antioxidant systems should be considered in future research. View Full-Text
Keywords: mineral; calcium; periodontitis; oral health; diet; nutrition mineral; calcium; periodontitis; oral health; diet; nutrition
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Varela-López, A.; Giampieri, F.; Bullón, P.; Battino, M.; Quiles, J.L. A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease. Molecules 2016, 21, 1183.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top