New Sesquiterpenenoids from Ainsliaea yunnanensis
AbstractInvestigation of the ethanol extract of the whole plant of Ainsliaea yunnanensis led to the isolation of four new dimeric sesquiterpene lactones, ainsliadimer F–I (1–4), together with seven known dimeric sesquiterpene lactones (5–11) and ten sesquiterpenes (12–21). Their structures were elucidated by spectroscopic methods. The relative stereochemistry of ainsliadimer F was further confirmed by single crystal X-ray diffraction analysis. Compounds 1–21 were tested for the inhibition of nuclear factor kappa B (NF-κB) in the 293-NF-κB-luciferase reporter cell line induced by lipopolysaccharide (LPS), and Compounds 5, 18, 20 and 21 were further tested for the production of TNF-α, IL-1β, IL-6 and IL-10 in RAW 264.7 macrophages induced by LPS. Compounds 5, 18, 20 and 21 exhibited significant activity in anti-inflammatory activity assays. View Full-Text
- Supplementary File 1:
PDF-Document (PDF, 1703 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Wu, X.-L.; Xiong, X.-J.; Lu, W.-Q.; Huang, H.; Shen, Y.-H.; Wu, Z.-J.; Chen, W.-S. New Sesquiterpenenoids from Ainsliaea yunnanensis. Molecules 2016, 21, 1031.
Wu X-L, Xiong X-J, Lu W-Q, Huang H, Shen Y-H, Wu Z-J, Chen W-S. New Sesquiterpenenoids from Ainsliaea yunnanensis. Molecules. 2016; 21(8):1031.Chicago/Turabian Style
Wu, Xiang-Lei; Xiong, Xiao-Juan; Lu, Wen-Quan; Huang, Hao; Shen, Yun-Heng; Wu, Zhi-Jun; Chen, Wan-Sheng. 2016. "New Sesquiterpenenoids from Ainsliaea yunnanensis." Molecules 21, no. 8: 1031.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.