Next Article in Journal
Metabolomic Profiles of Aspergillus oryzae and Bacillus amyloliquefaciens During Rice Koji Fermentation
Previous Article in Journal
Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
Article Menu
Issue 6 (June) cover image

Export Article

Open AccessArticle
Molecules 2016, 21(6), 774; doi:10.3390/molecules21060774

Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties

1
Department of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa
2
1124 Buchanan Street, Ginsburg, King William’s Town 5601, Eastern Cape, South Africa
3
Department of Physiology, Faculty of Health Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, Mthatha 5117, South Africa
4
Department of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, P. Bag X1, Mthatha 5117, South Africa
5
Department of Biological and Environmental Science Chemistry, Faculty of Natural Science, Walter Sisulu University, Nelson Mandela Drive Campus, P. BagX1, Mthatha 5117, South Africa
6
Centre for Nanomaterials Science Research, University of Johannesburg, Johannesburg Doornfontein 2028, South Africa
7
Department of Applied Chemistry, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Doornfontein 2028, Gauteng, South Africa
*
Authors to whom correspondence should be addressed.
Academic Editors: Alexandru Mihai Grumezescu and Derek J. Mcphee
Received: 20 March 2016 / Revised: 4 June 2016 / Accepted: 7 June 2016 / Published: 14 June 2016
(This article belongs to the Section Medicinal Chemistry)
View Full-Text   |   Download PDF [6017 KB, uploaded 14 June 2016]   |  

Abstract

We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver nanoparticles. Phytochemical screening of the ethanolic extract revealed the presence of glycosides, proteins, tannins, alkaloids, flavonoids and saponins. The absorption spectra showed that the synthesis is temperature and time dependent. The TEM analysis showed that the as-synthesised Ag-NPs are polydispersed and spherical in shape with average particle diameter of 19.95 ± 7.76 nm while the FTIR results confirmed the reduction and capping of the as-synthesised Ag-NPs by the phytochemicals present in the ethanolic extract. The analgesic study indicated that the combined effect of the plant extract and Ag-NPs is more effective in pain management than both the aspirin drug and the extract alone. View Full-Text
Keywords: silver nanoparticles; analgesic activity; phytochemicals; buchu silver nanoparticles; analgesic activity; phytochemicals; buchu
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chiguvare, H.; Oyedeji, O.O.; Matewu, R.; Aremu, O.; Oyemitan, I.A.; Oyedeji, A.O.; Nkeh-Chungag, B.N.; Songca, S.P.; Mohan, S.; Oluwafemi, O.S. Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties. Molecules 2016, 21, 774.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top