A New Megastigmane Sesquiterpenoid from Zanthoxylum Schinifolium Sieb. et Zucc
AbstractZanthoxylum schinifolium Sieb. et Zucc. (Rutaceae), a dioecious shrub with hooked prickly branches, has been used as folk medicine for the treatment of the common cold, stomach ache, diarrhea, and jaundice in China, Korea, and Japan. In our phytochemical investigations on this genus, a new megastigmane sesquiterpenoid, which is referred to as schinifolenol A (1), was isolated from Z. schinifolium. The stereochemistry was characterized via the analyses of extensive spectra. The absolute configuration was established by the application of a modified Mosher’s experiment and assisted by a time-dependent density functional theory (TD-DFT) on calculated electronic circular dichroism (ECD). Bioactivity screenings showed that compound 1 exhibited a safe hypotoxicity and a better selectivity on anti-Kaposi’s sarcoma associated herpes virus (KSHV).
- Supplementary File 1:
PDF-Document (PDF, 992 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Hu, L.; Wang, K.; Wang, Z.; Liu, J.; Wang, K.; Zhang, J.; Luo, Z.; Xue, Y.; Zhang, Y.; Zhang, Y. A New Megastigmane Sesquiterpenoid from Zanthoxylum Schinifolium Sieb. et Zucc. Molecules 2016, 21, 383.
Hu L, Wang K, Wang Z, Liu J, Wang K, Zhang J, Luo Z, Xue Y, Zhang Y, Zhang Y. A New Megastigmane Sesquiterpenoid from Zanthoxylum Schinifolium Sieb. et Zucc. Molecules. 2016; 21(3):383.Chicago/Turabian Style
Hu, Linzhen; Wang, Kongchao; Wang, Zhenzhen; Liu, Junjun; Wang, Kaiping; Zhang, Jinwen; Luo, Zengwei; Xue, Yongbo; Zhang, Yu; Zhang, Yonghui. 2016. "A New Megastigmane Sesquiterpenoid from Zanthoxylum Schinifolium Sieb. et Zucc." Molecules 21, no. 3: 383.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.