Molecules 2016, 21(3), 292; doi:10.3390/molecules21030292
Modified Polyacrylic Acid-Zinc Composites: Synthesis, Characterization and Biological Activity
Mohammed Rafi Shaik, Mufsir Kuniyil, Mujeeb Khan, Naushad Ahmad, Abdulrahman Al-Warthan, Mohammed Rafiq H. Siddiqui
and Syed Farooq Adil *
and Syed Farooq Adil *
Department of Chemistry, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 6 January 2016 / Revised: 13 February 2016 / Accepted: 25 February 2016 / Published: 29 February 2016
(This article belongs to the Section Bioorganic Chemistry)
Abstract
Polyacrylic acid (PAA) is an important industrial chemical, which has been extensively applied in various fields, including for several biomedical purposes. In this study, we report the synthesis and modification of this polymer with various phenol imides, such as succinimide, phthalimide and 1,8-naphthalimide. The as-synthesized derivatives were used to prepare polymer metal composites by the reaction with Zn+2. These composites were characterized by using various techniques, including NMR, FT-IR, TGA, SEM and DSC. The as-prepared PAA-based composites were further evaluated for their anti-microbial properties against various pathogens, which include both Gram-positive and Gram-negative bacteria and different fungal strains. The synthesized composites have displayed considerable biocidal properties, ranging from mild to moderate activities against different strains tested. View Full-TextKeywords:
polyacrylic acid; zinc; metal composite; biological activity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Shaik, M.R.; Kuniyil, M.; Khan, M.; Ahmad, N.; Al-Warthan, A.; Siddiqui, M.R.H.; Adil, S.F. Modified Polyacrylic Acid-Zinc Composites: Synthesis, Characterization and Biological Activity. Molecules 2016, 21, 292.
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